ISCA明哲论坛:NO. 149 Optimal Enrollment in Late-Stage New Drug Development with Learning of Drug’s Efficacy for Group-Sequential Clinical Trials
本次讲座将介绍一种用于优化新药晚期临床试验患者入组率的动态规划模型,结合药物疗效学习与市场独占期不确定性,帮助制药企业降低研发成本并提升收益。
报告介绍
Managerial implications. Firms can use the properties of the value function
to select late-stage clinical trials for their drug-development project
portfolios. Firms can also use our optimal policy to guide patient recruitment
in their clinical trials considering competition from other drugs in the
marketplace.
报告人介绍
Dr. Zhili Tian is the Dunavant Endowed Associate Professor of Supply Chain
Management. An exceptional scholar, Dr. Tian actively collaborates with
industry partners and is deeply dedicated to student success. Previously,
he served as a faculty member in Transportation and Civil Engineering
at Tsinghua University, where he directed numerous research projects,
led state- and provincial-level transportation planning initiatives, and
secured multiple grants from the National Natural Science Foundation of
China.
